Trains from Rome Termini Station run to all parts of Italy including north to Tuscany. Tuscany Bike Tours and Wine and food tours are offered out of Florence. The tours visit villages in the Tuscany hills and base in villages and cities such as cortona, Siena, and Florence. Tuscany Bicycle and Wine Tours are best bets for visitors on a short visit. Tuscany guided bike trips can include wine tasting and visits to notable restaurants and cooking schools.

Tuscany Walking, and Wine Tours are guided hikes or guided bike trips from village to village.

Tuscany Museums from Florence to Pisa offer the vacationer some great Museum visits. Florence is one of Italy's greatest cities.

Tuscany Vacation, Rome to Pisa, Italy: A Tuscany Vacation from Rome to Pisa Italy offers great diversity: hiking, biking, and great museums. The area between Rome and Pisa is an agricultural region.

Reach Italy by air, high-speed train. cruise ship, or rental car.
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Rome is like an outdoor museum
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  Italy Travel, Reach Italy, Air, Cruise, High-Speed Train

Auto Rental Rome

Rome Rental cars are available at the airport or at many locations in the city. Rome is a wakable city so a vehicle is not always needed.

The best bet is to rent only if you will visit outlying cities. 
Parking and driving could be difficult in Rome

A nice side trip from Rome is the Tivoli Gardens

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Italy offers train service from Rome Termini Train Station with train shuttle to the airport (FCO) and high speed trains to many cities.
High speed roads also connect major cities.

  Rome Flights, Air Travel To Rome

Rome Rental Cars

 Trains In Itlay

Air travel To Rome

Air travel to Rome will arrive at Rome's FCO Airport, Leonardo da Vinci,  about 40 miles west of the city of Rome

Flights to Rome, Transfers: Air Travel to Rome FCO Leonardo Da Vinci Airport is a big sprawling terminal about a forty minute drive south west of Rome. The airport offers hotels, rental autos, and train service to the city of Rome. Cruise ships reach Rome and high-speed trains serve to Rome's Termini Train Station

A car rental will include options on Luggage space, standard shift, auto, deisel or gas. Driving in Italy could require the International Driving Permit and familiarity with Traffic laws and international traffic symbols. Highway Driving, will be similar to highway driving in the US or Canada.